Vandetanib-d4

MedChem Express

Vandetanib-d4 [1215100-18-7]

10

1215100-18-7

Research Use Only

C22H20D4BrFN4O2

479.38

Vandetanib-d 4 is the deuterium labeled Vandetanib. Vandetanib (ZD6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM)[1][2].

N(C=1C2=C(C=C(OCC3CC(N(C)C(C3)([2H])[2H])([2H])[2H])C(OC)=C2)N=CN1)C4=C(F)C=C(Br)C=C4

12352200