Vandetanib-d6

MedChem Express

Vandetanib-d6 [1174683-49-8]

5

1174683-49-8

Research Use Only

C22H18D6BrFN4O2

481.39

Vandetanib-d 6 is the deuterium labeled Vandetanib. Vandetanib (D6474) is a potent, orally active inhibitor of VEGFR2/KDR tyrosine kinase activity (IC50=40 nM). Vandetanib also has activity versus the tyrosine kinase activity of VEGFR3/FLT4 (IC50=110 nM) and EGFR/HER1 (IC50=500 nM)[1].

FC1=CC(Br)=CC=C1NC2=NC=NC3=CC(OCC4CCN(CC4)C([2H])([2H])[2H])=C(C=C23)OC([2H])([2H])[2H]

12352200