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Vardenafil (hydrochloride trihydrate) (Standard)

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MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Vardenafil (hydrochloride trihydrate) (Standard)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Scientific Description
    Vardenafil (hydrochloride trihydrate) (Standard) is the analytical standard of Vardenafil (hydrochloride trihydrate). This product is intended for research and analytical applications. Vardenafil hydrochloride trihydrate is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride trihydrate shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4 [1] . Vardenafil hydrochloride trihydrate competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels [2] . Vardenafil hydrochloride trihydrate can be used for the research of erectile dysfunction, hepatitis, diabetes [1] - [6] .
  • UNSPSC
    41116135