Vatalanib (succinate)

MedChem Express

Vatalanib (succinate) [212142-18-2]

14

212142-18-2

Research Use Only

C24H21ClN4O4

464.90

Vatalanib (PTK787) succinate is a potent and orally active VEGFR inhibitor with IC 50 s of 37 nM, 77 nM, 270 nM, 660 nM, 730 nM, 1400 nM, and 580 nM for KDR, Flt-1, Flk, Flt-4, c-Kit, c-Fms, and PDGFR-beta, respectively [1] .

ClC(C=C1)=CC=C1NC2=C3C(C=CC=C3)=C(CC4=CC=NC=C4)N=N2.OC(CCC(O)=O)=O

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