Western Blot Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, HL-60 whole cell lysate, LO2 whole cell lysate, Raji whole cell lysate, Rat heart tissue, Mouse brain tissue All lanes: VDAC1 antibody at 0.7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 31 KDa Observed band size: 31 KDa
Western Blot Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, HL-60 whole cell lysate, LO2 whole cell lysate, Raji whole cell lysate, Rat heart tissue, Mouse brain tissue All lanes: VDAC1 antibody at 0.7microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 31 KDa Observed band size: 31 KDa
VDAC1 Recombinant Monoclonal Antibody
CSB-RA025821A0HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetVDAC1
Overview
- SupplierCusabio
- Product NameVDAC1 Recombinant Monoclonal Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID3A1
- ConjugateUnconjugated
- Gene ID7416
- Target nameVDAC1
- Target descriptionvoltage dependent anion channel 1
- Target synonymsouter mitochondrial membrane protein porin 1; plasmalemmal porin; PORIN; porin 31HL; porin 31HM; sperm binding protein 1a; VDAC-1; voltage-dependent anion-selective channel protein 1
- IsotypeIgG
- Protein IDP21796
- Protein NameVoltage-dependent anion-selective channel protein 1
- Scientific DescriptionForms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective (PubMed:11845315, PubMed:18755977, PubMed:20230784, PubMed:8420959). May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis (PubMed:15033708, PubMed:25296756).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203