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VEGF-R2 / CD309 / Flk-1 / KDR3(DC101), CF640R conjugate, 0.1mg/mL [26628-22-8]

VEGF-R2 / CD309 / Flk-1 / KDR3(DC101), CF640R conjugate, 0.1mg/mL [26628-22-8]

BNC400531
Biotium
ApplicationsFunctional Assay, Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityBovine, Mouse
TargetANGPT2
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Overview

  • Supplier
    Biotium
  • Product Name
    VEGF-R2 / CD309 / Flk-1 / KDR3(DC101), CF640R conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Functional Assay, Flow Cytometry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    DC101
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID285
  • Target name
    ANGPT2
  • Target description
    angiopoietin 2
  • Target synonyms
    AGPT2; ANG2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; LMPHM10; Tie2-ligand
  • Host
    Mouse
  • Isotype
    IgG1
  • Scientific Description
    This MAb is specific to Mouse VEGFR2/FLK-1/CD309 and does not cross-react with FLK-2. VEGFR2 is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Endothelial cells, embryonic tissues, and megakaryocytes mainly express VEGFR2. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGFR2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGFR2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203