
Activation assay analysis of HUVECs stimulated with 0.5, 1.0 and 2.0 microg/ml GTX52395 VEGF Receptor 2 antibody or 20ng/ml VEGF for 30mins. The phospho-VEGFR2 was detected with IP-Western for P-Tyrosine.
VEGF Receptor 2 antibody
GTX52395
ApplicationsImmunoPrecipitation, Western Blot, Other Application
Product group Antibodies
ReactivityHuman
TargetKDR
Overview
- SupplierGeneTex
- Product NameVEGF Receptor 2 antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier Note*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoPrecipitation, Western Blot, Other Application
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3791
- Target nameKDR
- Target descriptionkinase insert domain receptor
- Target synonymsCD309; fetal liver kinase-1; FLK1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor; vascular endothelial growth factor receptor 2; VEGFR; VEGFR2
- HostGoat
- IsotypeIgG
- Protein IDP35968
- Protein NameVascular endothelial growth factor receptor 2
- Scientific DescriptionVascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203