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VEGFR2 / Flk-1 / KDR3 / CD309(KDR657), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040657
Biotium
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetKDR
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Overview

  • Supplier
    Biotium
  • Product Name
    VEGFR2 / Flk-1 / KDR3 / CD309(KDR657), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    KDR657
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID3791
  • Target name
    KDR
  • Target description
    kinase insert domain receptor
  • Target synonyms
    CD309; fetal liver kinase-1; FLK1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor; vascular endothelial growth factor receptor 2; VEGFR; VEGFR2
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP35968
  • Protein Name
    Vascular endothelial growth factor receptor 2
  • Scientific Description
    CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203