VEGFR2 / Flk-1 / KDR3 / CD309(KDR657), CF640R conjugate, 0.1mg/mL [26628-22-8]
BNC400657
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetKDR
Overview
- SupplierBiotium
- Product NameVEGFR2 / Flk-1 / KDR3 / CD309(KDR657), CF640R conjugate, 0.1mg/mL
- Delivery Days Customer9
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDKDR657
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID3791
- Target nameKDR
- Target descriptionkinase insert domain receptor
- Target synonymsCD309; fetal liver kinase-1; FLK1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor; vascular endothelial growth factor receptor 2; VEGFR; VEGFR2
- HostMouse
- IsotypeIgG1
- Protein IDP35968
- Protein NameVascular endothelial growth factor receptor 2
- Scientific DescriptionCD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203