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Verdinexor [1392136-43-4]

HY-15970
MedChem Express
CAS Number1392136-43-4
Product group Chemicals
Estimated Purity99.94
Molecular Weight442.32
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Verdinexor [1392136-43-4]
  • Delivery Days Customer
    14
  • CAS Number
    1392136-43-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C18H12F6N6O
  • Molecular Weight
    442.32
  • Scientific Description
    Verdinexor (KPT-335) is an orally active inhibitor for selective inhibitor of nuclear export (SINE). Verdinexor inhibits the respiratory syncytial virus A2 (RSV A2) replication with an IC50 of 0.96 microM. Verdinexor inhibits the function of nuclear export protein Exportin 1 (XPO1/CRM1), inhibiting pro-inflammatory responses. Verdinexor exhibits antitumor effciency[1][2].
  • SMILES
    O=C(NNC1=NC=CC=C1)/C=C\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200