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ProductsBack/Verlukast [120443-16-5]
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Verlukast [120443-16-5]

Research Use Only
T19674
TargetMol Chemicals
CAS Number120443-16-5
DownloadMSDS
Product group Chemicals
Molecular Weight515.09
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Verlukast [120443-16-5]
  • Delivery Days Customer
    10
  • CAS Number
    120443-16-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Verlukast
  • Molecular Formula
    C26H27ClN2O3S2
  • Molecular Weight
    515.09
  • Scientific Description
    Verlukast is an (R)-enantiomer of MK-571 and a potent and selective LTD4 receptor antagonist. Verlukast showed [3H]leukotriene D4 binding in guinea-pig (IC50 = 3.1 +/- 0.5 nM) and human (IC50 = 8.0 +/- 3.0 nM) lung homogenates and dimethyl sulfoxide differentiated U937 cell membrane preparations (IC50 = 10.7 +/- 1.6 nM) but is essentially inactive versus [3H]leukotriene C4 binding in guinea-pig lung homogenates (IC50: 19 and 33 microM).
  • Shelf life instruction
    3 years
  • SMILES
    CN(C)C(=O)CCSC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200