VGSCs-IN-1

MedChem Express

VGSCs-IN-1 [1204296-79-6]

14

1204296-79-6

Research Use Only

C12H12F3N3OS

303.30

VGSCs-IN-1 (compound 14), a 2-piperazine analog of Riluzole (HY-B0211), is a human voltage-gated sodium channels (VGSCs) inhibitor. VGSCs-IN-1 shows great Nav1.4 blocking activity. VGSCs-IN-1 has a pKa of 7.6 and a cLog P of 2.4. VGSCs-IN-1 can be used for cell excitability disorders research [1] .

FC(F)(F)OC1=CC2=C(C=C1)N=C(N3CCNCC3)S2

12352200