VH032-O-C2-NH-Boc

MedChem Express

VH032-O-C2-NH-Boc

14

Research Use Only

C31H45N5O7S

631.78

VH032-O-C2-NH-Boc is a Boc-modified VH032 (HY-120217) that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-O-C2-NH-Boc will remove the protecting group under acidic conditions and can be directly used in PROTAC molecule synthesis. VH032-O-C2-NH-Boc is a key intermediate in the synthesis of PROTAC based on VHL ligand.

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(COCCNC(OC(C)(C)C)=O)=O)=O)C[C@H](O)C3

12352200