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Vimentin(VM452), CF405S conjugate, 0.1mg/mL [26628-22-8]

Vimentin(VM452), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC040452
Biotium
ApplicationsFlow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Canine, Chicken, Feline, Goat, Human, Mouse, Porcine
TargetVIM
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Overview

  • Supplier
    Biotium
  • Product Name
    Vimentin(VM452), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    Flow Cytometry, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    VM452
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID7431
  • Target name
    VIM
  • Target description
    vimentin
  • Target synonyms
    epididymis secretory sperm binding protein; vimentin
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP08670
  • Protein Name
    Vimentin
  • Scientific Description
    This MAb reacts with a 58 kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFPs) such as desmin, keratin, neurofilament, and glial fibrillary acid protein.Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Canine, Chicken, Feline, Goat, Human, Mouse, Porcine
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203