Vimirogant hydrochloride

TargetMol Chemicals

Vimirogant hydrochloride

114

Chemical

Research Use Only

Vimirogant hydrochloride

C27H36ClF3N4O3S

Vimirogant (VTP-43742) hydrochloride is an orally active, selective RORgammat inhibitor (IC50: 17 nM, Ki: 3.5 nM) that is more than 1000 times more selective than RORalpha and RORbeta. It inhibits Th17 differentiation and IL-17A secretion in mouse spleen cells with an IC50 of 57 nM and does not affect Th1, Th2, or Treg cell differentiation.

3 years

-20°C

12352200