![Vinculin (Marker of Age-related Macular Degeneration)(VCL/2573), CF405S conjugate, 0.1mg/mL [26628-22-8] Vinculin (Marker of Age-related Macular Degeneration)(VCL/2573), CF405S conjugate, 0.1mg/mL [26628-22-8]](https://biotium.com/wp-content/uploads/2021/02/view_image-914.jpeg)
Vinculin (Marker of Age-related Macular Degeneration)(VCL/2573), CF405S conjugate, 0.1mg/mL [26628-22-8]
BNC042573
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetVCL
Overview
- SupplierBiotium
- Product NameVinculin (Marker of Age-related Macular Degeneration)(VCL/2573), CF405S conjugate, 0.1mg/mL
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDVCL/2573
- Concentration0.1 mg/ml
- ConjugateOther Conjugate
- Gene ID7414
- Target nameVCL
- Target descriptionvinculin
- Target synonymsCMD1W; CMH15; epididymis luminal protein 114; epididymis secretory sperm binding protein; HEL114; metavinculin; meta-vinculin; MV; MVCL; vinculin; vinculin isoform meta-VCL
- HostMouse
- IsotypeIgG1
- Protein IDP18206
- Protein NameVinculin
- Scientific DescriptionFocal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including talin and alpha-actinin each contain actin binding sites. Reportedly, vinculin is a potential plasma biomarker for Age-related Macular Degeneration (AMD). The early detection of AMD using novel plasma biomarkers with genetic modeling may enable timely treatment and vision preservation in the elderly. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- SourceAnimal
- ReactivityBovine, Human, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203