Chemical Structure
Viridicatumtoxin [39277-41-3]
AG-CN2-0172
Overview
- SupplierAdipoGen Life Sciences
- Product NameViridicatumtoxin [39277-41-3]
- Delivery Days Customer10
- ADR Class6.1
- CAS Number39277-41-3
- CertificationResearch Use Only
- Estimated Purity>95%
- Hazard InformationWarning
- Molecular FormulaC30H31NO10
- Molecular Weight565.6
- Scientific DescriptionChemical. CAS: 39277-41-3. Formula: C30H31NO10. MW: 565.6. Isolated from Penicillium brasilianum. Mycotoxin. Tetracycline antibiotic. Potent antibacterial agent with activity against several strains of Staphylococcus aureus, including Methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA). Inhibits bacterial undecaprenyl pyrophosphate (UPP) synthase activity. Modest antitumor agent against selected cancer cell lines (IC50~1microM). - Mycotoxin. Tetracycline antibiotic. Potent antibacterial agent with activity against several strains of Staphylococcus aureus, including Methicillin-resistant S. aureus (MRSA) and quinolone-resistant S. aureus (QRSA). Inhibits bacterial undecaprenyl pyrophosphate (UPP) synthase activity. Modest antitumor agent against selected cancer cell lines (IC50~1microM).
- SMILESOC(C[C@]1(O)[C@@H](O)C2=C(C[C@]34C(C)=CCCC4(C)C)C(C3=C(OC)C=C5O)=C5C(O)=C2C6=O)=C(C(N)=O)C([C@]16O)=O
- Storage Instruction-20°C,2°C to 8°C
- UN Number2811
- UNSPSC12352200
References
- Viridicatumtoxin, a new mycotoxin from Penicillium viridicatum Westling: R.D. Hutchison, et al.; Toxicol. Appl. Pharmacol. 24, 507 (1973)
- Microbial transformations of natural antitumor agents. 20. Glucosylation of Viridicatumtoxin: M.S. Raju, et al.; J. Nat. Prod. 45, 321 (1982)
- Viridicatumtoxin mycotoxicosis in mice and rats: A.M. Bendele, et al.; Toxicol. Lett. 22, 287 (1984)
- Viridicatumtoxin B, a new anti-MRSA agent from Penicillium sp. FR11: C.J. Zheng, et al.; J. Antibiot. 61, 633 (2008)
- Viridicatumtoxins: Expanding on a Rare Tetracycline Antibiotic Scaffold: T. Shang, et al.; J. Org. Chem. 80, 12501 (2015)
- Inhibition of bacterial undecaprenyl pyrophosphate synthase by small fungal molecules: J. Inokoshi, et al.; J. Antibiot. 69,798 (2016)