VMP1 Polyclonal Antibody
RD266489A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetVMP1
Overview
- SupplierReddot Biotech
- Product NameVMP1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID81671
- Target nameVMP1
- Target descriptionvacuole membrane protein 1
- Target synonymsectopic P-granules autophagy protein 3 homolog; EPG3; TANGO5; TMEM49; transmembrane protein 49; transport and golgi organization 5 homolog; vacuole membrane protein 1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionVMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203