(-)-Voacangarine [545-84-6]

TargetMol Chemicals

(-)-Voacangarine [545-84-6]

999

Chemical

Research Use Only

(−)-Voacangarine

C22H28N2O4

384.47

(-)-Voacangarine, an indole alkaloid isolated from V. africana, exhibits cytotoxicity towards various cell lines including HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 values of 20 microg/ml. Additionally, it demonstrates cytostatic effects on wild-type S. cerevisiae and is cytotoxic to deltarad3-e5 and deltarad6-1 mutant strains of S. cerevisiae, which have defects in DNA strand break repair and the mutagenic repair pathway, respectively.

3 years

C(OC)(=O)[C@]12C3=C(C=4C(N3)=CC=C(OC)C4)CC[N@@]5[C@]1([C@@]([C@H](C)O)(C[C@](C2)(C5)[H])[H])[H]

-20°C

12352200