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VU0357017 (hydrochloride)

HY-19752A
MedChem Express
CAS Number1135242-13-5
Product group Chemicals
Estimated Purity99.91
Molecular Weight369.89
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VU0357017 (hydrochloride) [1135242-13-5]
  • Delivery Days Customer
    10
  • CAS Number
    1135242-13-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.91
  • Molecular Formula
    C18H28ClN3O3
  • Molecular Weight
    369.89
  • Scientific Description
    VU0357017 hydrochloride (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 hydrochloride is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 microM). VU0357017 hydrochloride can be used for the research of Alzheimers disease and schizophrenia[1][2][3].
  • SMILES
    O=C(N1CCC(NCCNC(C2=CC=CC=C2C)=O)CC1)OCC.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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References
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