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VU0364770

HY-100588
MedChem Express
CAS Number61350-00-3
Product group Chemicals
Estimated Purity99.94
Molecular Weight232.67
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VU0364770 [61350-00-3]
  • Delivery Days Customer
    10
  • CAS Number
    61350-00-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C12H9ClN2O
  • Molecular Weight
    232.67
  • Scientific Description
    VU0364770 is a selective and potent positive allosteric modulator (PAM) of mGlu4. VU0346770 exhibits EC50s of 290 nM and 1.1 microM at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 exhibits antagonist activity at mGlu5 with a potency of 17.9 microM and PAM activity at mGlu6 with a potency of 6.8 microM. VU0364770 also possesses activity at MAO with Ki values of 8.5 and 0.72 microM for human MAO-A and human MAO-B, respectively[1].
  • SMILES
    O=C(C1=NC=CC=C1)NC2=CC=CC(Cl)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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