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VU0364770

HY-100588
MedChem Express
CAS Number61350-00-3
DownloadMSDS
Product group Chemicals
Estimated Purity99.94
Molecular Weight232.67
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VU0364770 [61350-00-3]
  • Delivery Days Customer
    10
  • CAS Number
    61350-00-3
  • Estimated Purity
    99.94
  • Molecular Formula
    C12H9ClN2O
  • Molecular Weight
    232.67
  • Scientific Description
    VU0364770 is a selective and potent positive allosteric modulator ( PAM ) of mGlu4 . VU0346770 exhibits EC 50 s of 290 nM and 1.1 microM at rat mGlu4 and human mGlu4 receptor , respectively. VU0364770 exhibits antagonist activity at mGlu5 with a potency of 17.9 microM and PAM activity at mGlu6 with a potency of 6.8 microM. VU0364770 also possesses activity at MAO with K i values of 8.5 and 0.72 microM for human MAO-A and human MAO-B, respectively [1] .
  • SMILES
    O=C(C1=NC=CC=C1)NC2=CC=CC(Cl)=C2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200