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VU0364770 (hydrochloride)

HY-100588A
MedChem Express
CAS Number1414842-70-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.70
Molecular Weight269.13
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VU0364770 (hydrochloride) [1414842-70-8]
  • Delivery Days Customer
    10
  • CAS Number
    1414842-70-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.70
  • Molecular Formula
    C12H10Cl2N2O
  • Molecular Weight
    269.13
  • Scientific Description
    VU0364770 hydrochloride is a selective and potent positive allosteric modulator (PAM) of mGlu4. VU0346770 hydrochloride exhibits EC50s of 290 nM and 1.1 microM at rat mGlu4 and human mGlu4 receptor, respectively. VU0364770 hydrochloride exhibits antagonist activity at mGlu5 with a potency of 17.9 microM and PAM activity at mGlu6 with a potency of 6.8 microM. VU0364770 hydrochloride also possesses activity at MAO with Ki values of 8.5 and 0.72 microM for human MAO-A and human MAO-B, respectively[1].
  • SMILES
    O=C(C1=NC=CC=C1)NC2=CC=CC(Cl)=C2.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200

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VU0364770 hydrochloride [1414842-70-8]
Product group Chemicals
TargetMol Chemicals
VU0364770 hydrochloride [1414842-70-8]T13317
CAS Number1414842-70-8
Molecular Weight269.13
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