VU0409106

MedChem Express

VU0409106 [1276617-62-9]

10

1276617-62-9

Research Use Only

99.76

C15H11FN4O2S

330.34

VU0409106 is a potent and selective mGlu 5 negative allosteric modulator (NAM) with an IC 50 of 24 nM. VU0409106 shows anxiolytic effects in rat models in a concentration-dependent manner. VU0409106 also penetrates the blood-brain barrier (BBB) [1] [2] .

CC1=CSC(NC(C2=CC(F)=CC(OC3=CN=CN=C3)=C2)=O)=N1

-20°C,2°C to 8°C

12352200