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ProductsBack/VU0463271 [1391737-01-1]
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VU0463271 [1391737-01-1]

Research Use Only
T17243
TargetMol Chemicals
CAS Number1391737-01-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.75%
Molecular Weight382.5
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    VU0463271 [1391737-01-1]
  • Delivery Days Customer
    4
  • CAS Number
    1391737-01-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    VU0463271
  • Estimated Purity
    99.75%
  • Molecular Formula
    C19H18N4OS2
  • Molecular Weight
    382.5
  • Scientific Description
    VU0463271 (N-Cyclopropyl-N-(4-methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]acetamide) is a potent and selective antagonist of the neuronal-specific potassium-chloride cotransporter 2 (KCC2), with an IC50 of 61 nM and >100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1) and no activity in a larger panel of GPCRs, ion channels, and transporters.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1csc(n1)N(C1CC1)C(=O)CSc1ccc(nn1)-c1ccccc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200