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ProductsBack/W-5 . hydrochloride [61714-25-8]
Chemical Structure
Chemical Structure
Chemical Structure

W-5 . hydrochloride [61714-25-8]

Research Use Only
AG-CR1-0003
AdipoGen Life Sciences
CAS Number61714-25-8
DownloadMSDS
Product group Chemicals
Estimated Purity>98%
Molecular Weight306.4 . 36.5
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    W-5 . hydrochloride [61714-25-8]
  • Delivery Days Customer
    10
  • CAS Number
    61714-25-8
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Molecular Formula
    C16H22N2O2S . HCl
  • Molecular Weight
    306.4 . 36.5
  • Scientific Description
    Calmodulin antagonist [1-3]. Cell proliferation inhibitor [1]. Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor [3]. Myosin light chain kinase (MLCK) inhibitor [4]. - Chemical. CAS: 61714-25-8. Formula: C16H22N2O2S . HCl. MW: 306.4 . 36.5. Calmodulin antagonist. Cell proliferation inhibitor. Ca2+/calmodulin-regulated phosphodiesterase (PDE I) inhibitor. Myosin light chain kinase (MLCK) inhibitor.
  • SMILES
    [Cl-].[NH3+]CCCCCCNS(=O)(=O)C1=C2C=CC=CC2=CC=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation: H. Hidaka, et al.; PNAS 78, 4354 (1981)
  • W-5 and quin 2-AM reverse the inhibitory effect of insulin on lipolysis due to dibutyryl cAMP: H. Goko & A. Matsuoka; Diabetes Res. Clin. Pract. 44, 101 (1999)
  • Calmodulin antagonism and growth-inhibiting activity of triphenylethylene antiestrogens in MCF-7 human breast cancer cells: A. Gulino, et al.; Cancer Res. 46, 6274 (1986)
  • Hydrophobic regions function in calmodulin-enzyme(s) interactions.: T. Tanaka & H. Hidaka ; J. Biol. Chem. 255, 11078 (1980)