WAY-213613

AbMole BioScience

WAY-213613

9

868359-05-1

Chemical

Research Use Only

C16H13BrF2N2O4

415.19

Way-213613 is a potent, selective, non-substrate reuptake inhibitor of GLT-1/EAAT2 with an IC50 of 85 nM against EAAT2. The selectivity of WAY-213613 hydrochloride to EAAT1 and EAAT3 was 59 and 44 times higher (IC50 was 5 and 3.8 uM, respectively). Way-213613 has no activity on ionic and metabolic glutamate receptors.

NC(CC(=O)NC1=CC=C(OC2=C(Br)C=C(F)C(=C2)F)C=C1)C(O)=O

12352200