WBSCR22 antibody
GTX105840
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetBUD23
Overview
- SupplierGeneTex
- Product NameWBSCR22 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:500-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.42 mg/ml
- ConjugateUnconjugated
- Gene ID114049
- Target nameBUD23
- Target descriptionBUD23 rRNA methyltransferase and ribosome maturation factor
- Target synonymsHASJ4442, HUSSY-3, MERM1, PP3381, WBMT, WBSCR22, 18S rRNA (guanine-N(7))-methyltransferase, Williams-Beuren candidate region putative methyltransferase, Williams-Beuren syndrome chromosomal region 22 protein, Williams-Beuren syndrome chromosome region 22, bud site selection protein 23 homolog, metastasis-related methyltransferase 1, probable 18S rRNA (guanine-N(7))-methyltransferase, rRNA methyltransferase and ribosome maturation factor, ribosome biogenesis methyltransferase WBSCR22
- HostRabbit
- IsotypeIgG
- Protein IDO43709
- Protein Name18S rRNA (guanine-N(7))-methyltransferase
- Scientific DescriptionThis gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Zhao H, Su W, Sun Y, et al. WBSCR22 Competes with Long Non-coding RNA Linc00346 for miR-509-5p Binding Site to Regulate Cancer Stem Cell Phenotypes of Colorectal Cancer. Biochem Genet. 2020,58(3):384-398. doi: 10.1007/s10528-020-09949-yRead this paper
- Baxter M, Voronkov M, Poolman T, et al. Cardiac mitochondrial function depends on BUD23 mediated ribosome programming. Elife. 2020,9. doi: 10.7554/eLife.50705Read this paper
- Zhao H, Su W, Kang Q, et al. Natural killer cells inhibit oxaliplatin-resistant colorectal cancer by repressing WBSCR22 via upregulating microRNA-146b-5p. Am J Cancer Res. 2018,8(5):824-834.Read this paper
- Nakazawa Y, Arai H, Fujita N. The novel metastasis promoter Merm1/Wbscr22 enhances tumor cell survival in the vasculature by suppressing Zac1/p53-dependent apoptosis. Cancer Res. 2011,71(3):1146-55. doi: 10.1158/0008-5472.CAN-10-2695Read this paper



