WDFY2 Antibody, Biotin conjugated

Cusabio

WDFY2 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

WDFY2

WD repeat and FYVE domain containing 2

PROF; propeller-FYVE protein; WD repeat and FYVE domain-containing protein 2; WD40 and FYVE domain containing 2; WD40- and FYVE domain-containing protein 2; WDF2; ZFYVE22; zinc finger FYVE domain-containing protein 22

Rabbit

IgG

WD repeat and FYVE domain-containing protein 2

Acts in an adapter protein-like fashion to mediate the interaction between the kinase PRKCZ and its substrate VAMP2 and increases the PRKCZ-dependent phosphorylation of VAMP2 (PubMed:17313651). Positively regulates adipocyte differentiation, by facilitating the phosphorylation and thus inactivation of the anti-adipogenetic transcription factor FOXO1 by the kinase AKT1 (PubMed:18388859). Plays a role in endosomal control of AKT2 signaling; required for insulin-stimulated AKT2 phosphorylation and glucose uptake and insulin-stimulated phosphorylation of AKT2 substrates (By similarity). Participates in transferrin receptor endocytosis (PubMed:16873553).

Human

-20°C or -80°C

12352203