Bio-Connect

WDR24 antibody

GTX133576
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetWDR24
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    GeneTex
  • Product Name
    WDR24 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    4.38 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID84219
  • Target name
    WDR24
  • Target description
    WD repeat domain 24
  • Target synonyms
    C16orf21; GATOR complex protein WDR24; JFP7; WD repeat-containing protein 24
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96S15
  • Protein Name
    GATOR complex protein WDR24
  • Scientific Description
    As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway (PubMed:23723238, PubMed:27166823). Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:26449471, PubMed:26586190, PubMed:27487210). In addition to its role in regulation of the TORC1 complex, promotes the acidification of lysosomes and facilitates autophagic flux (PubMed:27166823).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203