WDR34 Antibody, HRP conjugated
CSB-PA842668LB01HU
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetDYNC2I2
Overview
- SupplierCusabio
- Product NameWDR34 Antibody, HRP conjugated
- Delivery Days Customer20
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateHRP
- FormulationLiquid
- Gene ID89891
- Target nameDYNC2I2
- Target descriptiondynein 2 intermediate chain 2
- Target synonymsbA216B9.3; CFAP133; cytoplasmic dynein 2 intermediate chain 2; DIC5; FAP133; SRTD11; WD repeat domain 34; WD repeat-containing protein 34; WDR34
- HostRabbit
- IsotypeIgG
- Protein IDQ96EX3
- Protein NameWD repeat-containing protein 34
- Scientific DescriptionCritical for ciliary functions, essential to normal development and survival, most probably as a previously unrecognized component of the mammalian dynein-motor-based intraflagellar transport (IFT) machinery. Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Inhibits the MAP3K7-induced NF-kappa-B activation pathway. Inhibits MAP3K7 phosphorylation at \\\Thr-184\\\ and \\\Thr-187\\\ upon Il-1 beta stimulation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203