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ProductsBack/WDR41 Antibody, Biotin conjugated

WDR41 Antibody, Biotin conjugated

Research Use Only
CSB-PA864011LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetWDR41
Price on request
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Cusabio
  • Product Name
    WDR41 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID55255
  • Target name
    WDR41
  • Target description
    WD repeat domain 41
  • Target synonyms
    MSTP048; WD repeat-containing protein 41
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9HAD4
  • Protein Name
    WD repeat-containing protein 41
  • Scientific Description
    Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy (PubMed:27193190, PubMed:27103069, PubMed:27617292, PubMed:28195531). The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (PubMed:27103069). The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity (PubMed:27103069, PubMed:27617292).
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203