WDSUB1 Polyclonal Antibody

Reddot Biotech

WDSUB1 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.7 mg/ml

Unconjugated

WDSUB1

WD repeat, sterile alpha motif and U-box domain containing 1

UBOX6; WD repeat, SAM and U-box domain-containing protein 1; WDSAM1

Rabbit

IgG

WDSUB1 (WD repeat, SAM and U-box domain-containing protein 1), also known as UBOX6 or WDSAM1, is a 476 amino acid protein that contains one SAM (sterile alpha motif) domain, one U-box domain and seven WD repeats. Existing as two isoforms due to alternative splicing, WDSUB1 is encoded by a gene located on chromosome 2. The second largest human chromosome, chromosome 2 encodes over 1,400 genes and comprises nearly 8% of the human genome, housing a number of disease-associated genes. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstrm syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

Human, Mouse

-20°C

12352203