WHSC1 antibody

Biorbyt

WHSC1 antibody

16

Western Blot

WB:1:500-1:1000 WB

Research Use Only

Polyclonal

Unconjugated

NSD2

nuclear receptor binding SET domain protein 2

histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; KMT3F; KMT3G; MMSET; multiple myeloma SET domain containing protein type III; nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; REIIBP; trithorax/ash1-related protein 5; TRX5; WHS; WHSC1; Wolf-Hirschhorn syndrome candidate 1

Rabbit

Histone-lysine N-methyltransferase NSD2

Rabbit polyclonal to WHSC1.Wolf-Hirschhorn syndrome candidate 1 protein (WHSC1) is a probable histone methyltransferasewhich may act as a transcription regulator that binds DNA and suppresses IL5 transcription. WHSC1contains four domains present in other developmental proteins: a PWWP domain, an HMG box, aSET domain and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion ofthe distal short arm of chromosome 4. The WHSC1 gene maps to the 165 kb WHS critical region andhas also been implicated in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas.Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

Human

-20°C

12352203