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Western blot All lanes: WIPI1 antibody at 6ug/ml Lane 1: 293T whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lane 3: Mouse skeletal muscle tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49 kDa Observed band size: 49 kDa
Western blot All lanes: WIPI1 antibody at 6ug/ml Lane 1: 293T whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lane 3: Mouse skeletal muscle tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49 kDa Observed band size: 49 kDa
Western blot All lanes: WIPI1 antibody at 6ug/ml Lane 1: 293T whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lane 3: Mouse skeletal muscle tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49 kDa Observed band size: 49 kDa

WIPI1 Antibody

Research Use Only
CSB-PA705810ESR2HU
Cusabio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetWIPI1
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Overview

  • Supplier
    Cusabio
  • Product Name
    WIPI1 Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID55062
  • Target name
    WIPI1
  • Target description
    WD repeat domain, phosphoinositide interacting 1
  • Target synonyms
    ATG18; atg18 protein homolog; ATG18A; WD repeat domain phosphoinositide-interacting protein 1; WIPI-1 alpha; WIPI49
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ5MNZ9
  • Protein Name
    WD repeat domain phosphoinositide-interacting protein 1
  • Scientific Description
    Plays an important role in autophagy and in particular starvation- and calcium-mediated autophagy, as well as in mitophagy. Functions upstream of the ATG12-ATG5-ATG16L1 complex and LC3, and downstream of the ULK1 and PI3-kinase complexes. Involved in xenophagy of Staphylococcus aureus. Invading S.aureus cells become entrapped in autophagosome-like WIPI1 positive vesicles targeted for lysosomal degradation. Plays also a distinct role in controlling the transcription of melanogenic enzymes and melanosome maturation, a process that is distinct from starvation-induced autophagy. May also regulate the trafficking of proteins involved in the mannose-6-phosphate receptor (MPR) recycling pathway.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203