WK499

TargetMol Chemicals

WK499

999

Chemical

Research Use Only

WK499

C21H20BrN7O3

498.33

BCL6-IN-10 (Compound WK499) is an inhibitor of BCL6 that disrupts its interaction with the SMRT protein, promoting apoptosis, cell cycle arrest, and DNA damage. It effectively hampers the proliferation of various AML cell lines, with IC50 values of 0.91, 1.63, 1.026, 7.42, 0.87, and 0.85 microM for OCI-AML3, THP1, MOLM13, HL60, KG1, and NB4 cells, respectively [1].

3 years

-20°C

12352200