WLB-89462

MedChem Express

WLB-89462

14

Research Use Only

98.07

C21H29N5O3

399.49

WLB-89462 (Compound 20c) is a selective sigma2 receptor ligand ( K i : 13 nM). WLB-89462 has neuroprotective activity. WLB-89462 improves short-term memory impairment induced by Abeta peptide in rats. WLB-89462 has good ADMET profile (good solubility, no CYP inhibition, good metabolic stability, high permeability, brain penetration, and high oral exposure in rodents) [1] .

O=C(CN1CCC(CC1)C2=C(C3=CC(C)=NO3)C=NC(CC)=N2)N4CCOCC4

-20°C

12352200