Wnt/beta-catenin-IN-3 [1809413-98-6]

TargetMol Chemicals

Wnt/beta-catenin-IN-3 [1809413-98-6]

16

Research Use Only

C26H23NO7

461.46

Wnt/beta-catenin-IN-3 (compound 17), a Wnt/beta-catenin inhibitor, exhibits low micromolar GI 50 s across different cancer cell lines. It induces G2/M cell cycle arrest through the activation of the p53-p21 pathway and promotes both intrinsic and extrinsic apoptotic death in colon cancer cells [1].

O(C)C1=C2C(OC(=CC2=O)C3=CC(NC(=O)C4=CC=C(OC)C=C4)=CC=C3)=CC(OC)=C1OC

-20°C

51202000