Wortmannin (KY 12420) [19545-26-7]
S2758
CAS Number19545-26-7
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameWortmannin (KY 12420) [19545-26-7]
- Delivery Days Customer9
- CAS Number19545-26-7
- CertificationResearch Use Only
- Scientific DescriptionWortmannin (KY 12420, SL-2052, BRN 0067676, NSC 627609) is the first described PI3K inhibitor with IC50 of 3 nM in a cell-free assay, with little selectivity within the PI3K family. Wortmannin blocks autophagosome formation and potently inhibits DNA-PK/ATM with IC50 of 16 nM and 150 nM in cell-free assays. Wortmannin also inhibits PLK1 activity.
- UNSPSC12352200
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