WRN inhibitor 7 [444780-45-4]

TargetMol Chemicals

WRN inhibitor 7 [444780-45-4]

16

Research Use Only

C27H23N3O6

485.49

WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRNs helicase and ATPase activities with IC50 values of 9.8 microM and 15.8 microM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].

C(=C1C(=O)N(CC(NC2=CC=C(C)C=C2)=O)C(=O)N1)C3=C(OCC4=CC(C(O)=O)=CC=C4)C=CC=C3

-20°C

51202000