WTAP Antibody
CSB-PA722026
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse
TargetWTAP
Overview
- SupplierCusabio
- Product NameWTAP Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID9589
- Target nameWTAP
- Target descriptionWT1 associated protein
- Target synonymsfemale-lethal(2)D homolog; hFL(2)D; Mum2; PNAS-132; pre-mRNA-splicing regulator WTAP; putative pre-mRNA splicing regulator female-lethal(2D); Wilms tumor 1 associated protein; wilms tumor 1-associating protein; Wilms' tumour 1-associating protein
- HostRabbit
- IsotypeIgG
- Protein IDQ15007
- Protein NamePre-mRNA-splicing regulator WTAP
- Scientific DescriptionRegulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine (m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing and processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle. Acts as a mRNA splicing regulator. Regulates G2/M cell-cycle transition by binding to the 3 UTR of CCNA2, which enhances its stability. Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes. Ortega A., J. Biol. Chem. 278:3040-3047(2003). Nagase T., DNA Res. 2:37-43(1995). Mungall A.J., Nature 425:805-811(2003).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203