WWOX Polyclonal Antibody

Reddot Biotech

WWOX Polyclonal Antibody

5

ImmunoFluorescence

Research Use Only

1 mg/ml

Unconjugated

WWOX

WW domain containing oxidoreductase

D16S432E; DEE28; EIEE28; FOR; FRA16D; fragile site FRA16D oxidoreductase; HHCMA56; PRO0128; SCAR12; SDR41C1; short chain dehydrogenase/reductase family 41C member 1; WOX1; WW domain-containing oxidoreductase; WW domain-containing protein WWOX

Rabbit

IgG

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) protein family. This gene spans the FRA16D common chromosomal fragile site and appears to function as a tumor suppressor gene. Expression of the encoded protein is able to induce apoptosis, while defects in this gene are associated with multiple types of cancer. Disruption of this gene is also associated with autosomal recessive spinocerebellar ataxia 12. Disruption of a similar gene in mouse results in impaired steroidogenesis, additionally suggesting a metabolic function for the protein. Alternative splicing results in multiple transcript variants.

Human, Mouse

-20°C

12352203