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ProductsBack/WWP2 Antibody, Biotin conjugated

WWP2 Antibody, Biotin conjugated

CSB-PA026168LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetWWP2
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Overview

  • Supplier
    Cusabio
  • Product Name
    WWP2 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID11060
  • Target name
    WWP2
  • Target description
    WW domain containing E3 ubiquitin protein ligase 2
  • Target synonyms
    AIP2; atrophin-1 interacting protein 2; HECT-type E3 ubiquitin transferase WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2; WWp2-like
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO00308
  • Protein Name
    NEDD4-like E3 ubiquitin-protein ligase WWP2
  • Scientific Description
    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by \\\Lys-63\\\-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203