XL01126

TargetMol Chemicals

XL01126

1001

Chemical

XL01126

C50H64ClFN10O6S2

1019.69

XL01126 is a potent degrader of LRRK2 with DC 50 s of 14 nM (G2019S LRRK2) and 32 nM (WT LRRK2), respectively. XL01126 can cross blood-brain barrier and be used as a degrader probe in Parkinson’s disease research. XL01126 exerts function of study of non-catalytic and scaffolding functions of LRRK2 [1] .

3 years

-20°

12352200