XSJ-10

MedChem Express

XSJ-10

14

Research Use Only

C21H26N2O8S

466.50

XSJ-10 is a HDAC inhibitor containing a RAS/RAF protein interfering unit, with IC 50 s of 0.05 and 0.04 microM in PANC-1 cells and HT-29 cells. XSJ-10 can effectively induce the apoptosis of cancer cells and suppress the tumor by strongly inhibiting the RAS-RAF-MEK-ERK signaling pathway and the acetylation level of HDAC3 [1] .

COC1=CC(OC)=C(C(OC)=C1)/C=C/S(CC2=CC=C(C(NCC(NO)=O)=C2)OC)(=O)=O

12352200