XVA143

MedChem Express

XVA143 [264275-77-6]

10

264275-77-6

Research Use Only

C25H21Cl2N3O8

562.36

XVA143, an alpha/beta I-like allosteric antagonist, inhibits LFA-1 dependent firm adhesion, while at the same time it enhances adhesion in shear flow and rolling both in vitro and in vivo[1].

O=C(O)[C@H](CNC(C1=CC(O)=CC(O)=C1)=O)NC(C2=C(Cl)C=C(C(NCC3=CC=CC(O)=C3)=O)C=C2Cl)=O

12352200