YBX1 Polyclonal Antibody

Reddot Biotech

YBX1 Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

YBX1

Y-box binding protein 1

BP-8; CBF-A; CCAAT-binding transcription factor I subunit A; CSDA2; CSDB; DBPB; DNA-binding protein B; EFI-A; enhancer factor I subunit A; major histocompatibility complex, class II, Y box-binding protein I; MDR-NF1; NSEP1; NSEP-1; nuclease-sensitive element-binding protein 1; YB1; YB-1; Y-box transcription factor; Y-box-binding protein 1

Rabbit

IgG

This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at Lys-6 and Lys-7. Binds to promoters that contain a Y-box (5-CTGATTGGCCAA-3), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).

Human, Mouse, Rat

-20°C

12352203