Overview
- SupplierBPS Bioscience
- Product NameYES1 Assay Kit
- Delivery Days Customer7
- CertificationResearch Use Only
- Scientific DescriptionProto-oncogene tyrosine-protein kinase YES1 has been implicated in regulation of cell growth and survival, apoptosis, cell-cell adhesion, and differentiation. It has been identified as a potential target in basal-like breast cancers. The YES1 Assay Kit is designed to measure YES1 activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent. The YES1 Assay Kit comes in a convenient 96-well format, with enough purified recombinant YES1 enzyme, Protein Tyrosine Kinase Substrate (Poly-Glu,Tyr 4:1), ATP, and kinase assay buffer for 100 enzyme reactions.
- UNSPSC41116133
References
- Hamamura K., Tsuji M., et al. Functional Activation of Src Family Kinase Yes Protein is Essential for the Enhanced Malignant Properties of Human Melanoma Cells Expressing Ganglioside GD3, 2011, J.] Biol. Chem.] 286: 18526-18537.
- Bilal, E., Alexe G., et al. Identification of the YES1 Kinase as a Therapeutic Target in Basal-Like Breast Cancers, 2010, Genes & Cancer Oct, 1(10): 1063-1073.
