Bio-Connect

YM-53601 free base

HY-100313
MedChem Express
CAS Number182959-28-0
Product group Chemicals
Molecular Weight336.40
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Overview

  • Supplier
    MedChem Express
  • Product Name
    YM-53601 free base [182959-28-0]
  • Delivery Days Customer
    10
  • CAS Number
    182959-28-0
  • Molecular Formula
    C21H21FN2O
  • Molecular Weight
    336.40
  • Scientific Description
    YM-53601 free base, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo [1] . YM-53601 free base inhibits squalene synthase derived from human hepatoma cells with an IC 50 of 79 nM. Lipid-lowering agent [2] . YM-53601 free base is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 ( FDFT1 ) enzyme activity and abrogates HCV propagation [3] .
  • SMILES
    F/C(COC1=CC(NC2=C3C=CC=C2)=C3C=C1)=C4CN5CCC/4CC5
  • UNSPSC
    51202000