YM-53601 free base
HY-100313
CAS Number182959-28-0
Product group Chemicals
Molecular Weight336.40
Overview
- SupplierMedChem Express
- Product NameYM-53601 free base [182959-28-0]
- Delivery Days Customer10
- CAS Number182959-28-0
- Molecular FormulaC21H21FN2O
- Molecular Weight336.40
- Scientific DescriptionYM-53601 free base, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo [1] . YM-53601 free base inhibits squalene synthase derived from human hepatoma cells with an IC 50 of 79 nM. Lipid-lowering agent [2] . YM-53601 free base is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 ( FDFT1 ) enzyme activity and abrogates HCV propagation [3] .
- SMILESF/C(COC1=CC(NC2=C3C=CC=C2)=C3C=C1)=C4CN5CCC/4CC5
- UNSPSC51202000