YS-363 [2470908-90-6]

TargetMol Chemicals

YS-363 [2470908-90-6]

16

Chemical

Research Use Only

YS-363

C30H30N4O3

494.58

YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), with half-maximal inhibitory concentrations (IC50) of 0.96 nM for the wild-type EGFR and 0.67 nM for the L858R mutant variant. It induces G0/G1 cell cycle arrest and apoptosis in targeted cells [1].

3 years

N=1C=NC(=C2C=C(OCCCN3CCOCC3)C(OC)=CC12)C=4C=5C=CC=CC5NC4C=6C=CC=CC6

-20°C

12352200