Z-Gly-Pro-Phe-Leu-CHO

MedChem Express

Z-Gly-Pro-Phe-Leu-CHO

14

Research Use Only

Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor ( K i = 1.5 microM for branched chain amino acid preferring, 2.3 microM for small neutral amino acid preferring, and 40.5 microM for chymotrypsin-like activities; IC 50 = 3.1 microM for peptidyl-glutamyl peptide hydrolyzing activity) [1] .

12352202